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Protein

Probable acyl-activating enzyme 8

Gene

AAE8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May act as an acid--thiol ligase that activates carboxylic acids by forming acyl-CoAs.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processFatty acid metabolism, Lipid metabolism

Enzyme and pathway databases

BioCyciARA:AT1G75960-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acyl-activating enzyme 8 (EC:6.2.1.-)
Alternative name(s):
AMP-binding protein 8
Short name:
AtAMPBP8
Gene namesi
Name:AAE8
Synonyms:AMPBP8
Ordered Locus Names:At1g75960
ORF Names:T4O12.18
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G75960
TAIRilocus:2204360 AT1G75960

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004157191 – 544Probable acyl-activating enzyme 8Add BLAST544

Proteomic databases

PaxDbiQ9LQS1

PTM databases

iPTMnetiQ9LQS1

Expressioni

Tissue specificityi

Expressed at low levels in roots, leaves, stems, flowers and developing seeds.1 Publication

Gene expression databases

ExpressionAtlasiQ9LQS1 baseline and differential
GenevisibleiQ9LQS1 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G75960.1

Structurei

3D structure databases

ProteinModelPortaliQ9LQS1
SMRiQ9LQS1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1176 Eukaryota
COG0318 LUCA
HOGENOMiHOG000230005
InParanoidiQ9LQS1
OMAiAREMGPT
OrthoDBiEOG093608HH
PhylomeDBiQ9LQS1

Family and domain databases

InterProiView protein in InterPro
IPR025110 AMP-bd_C
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
PfamiView protein in Pfam
PF00501 AMP-binding, 1 hit
PF13193 AMP-binding_C, 1 hit
PROSITEiView protein in PROSITE
PS00455 AMP_BINDING, 1 hit

Sequencei

Sequence statusi: Complete.

Q9LQS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDLKPSAAN SLPLTLLGFL ERAATVYGDC TSIVYGNSTV YTWRETNHRC
60 70 80 90 100
LCVASALSSI GIGRSDVVSV LSANTPEMYE LQFSVPMSGA ILNNINTRLD
110 120 130 140 150
ARTVSVLLRH CESKLLFVDF FYSDLAVEAI TMLLNPPILV LIANEEEEEG
160 170 180 190 200
GAEVTERSKF CYLYSDLITR GNPDFKWIRP GSEWDPIVVN YTSGTTSSPK
210 220 230 240 250
GVVHCHRGIF VMTLDSLTDW AVPKTPVYLW TLPIFHANGW TYPWGIAAVG
260 270 280 290 300
GTNVCVRKLH APSIYHLIRD HGVTHMYGAP IVLQILSASQ ESDQPLKSPV
310 320 330 340 350
NFLTAGSSPP ATVLLRAESL GFIVSHGYGL TETAGVIVSC AWKPNWNRLP
360 370 380 390 400
ASDQAQLKSR QGVRTVGFSE IDVVDPESGR SVERDGETVG EIVLRGSSIM
410 420 430 440 450
LGYLKNPIGT QNSFKNGWFF TGDLGVIHGD GYLEIKDRSK DVIISGGENV
460 470 480 490 500
SSVEVEAVLY TNPAVNEAAV VARPDEFWGE TPCAFVSLKP GLTRKPTDKE
510 520 530 540
IIEYCKYKMP RYMAPKTVSF LEELPKTSTG KIIKSLLKEI AKNM
Length:544
Mass (Da):59,711
Last modified:October 1, 2000 - v1
Checksum:i8A22CF91AFB3C66B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti3 – 5DLK → E in AAM28625 (PubMed:12177484).Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF503767 mRNA Translation: AAM28625.1
AC007396 Genomic DNA Translation: AAF26762.1
CP002684 Genomic DNA Translation: AEE35781.1
AY070450 mRNA Translation: AAL49853.1
AY142663 mRNA Translation: AAN13201.1
RefSeqiNP_177724.1, NM_106246.4
UniGeneiAt.28351
At.67201
At.71895

Genome annotation databases

EnsemblPlantsiAT1G75960.1; AT1G75960.1; AT1G75960
GeneIDi843929
GrameneiAT1G75960.1; AT1G75960.1; AT1G75960
KEGGiath:AT1G75960

Similar proteinsi

Entry informationi

Entry nameiAAE8_ARATH
AccessioniPrimary (citable) accession number: Q9LQS1
Secondary accession number(s): Q8LRT4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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