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Protein

Glutaredoxin-1

Gene

VACWR069

Organism
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Displays thioltransferase and dehydroascorbate reductase activities.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaredoxin-1
Gene namesi
Ordered Locus Names:VACWR069
ORF Names:O2L
OrganismiVaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Taxonomic identifieri10254 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePoxviridaeChordopoxvirinaeOrthopoxvirusVaccinia virus
Virus hostiBos taurus (Bovine) [TaxID: 9913]
Proteomesi
  • UP000000344 Componenti: Genome

Subcellular locationi

  • Virion 1 Publication
  • Note: Localizes to the virion core.Curated

GO - Cellular componenti

  • virion Source: UniProtKB-SubCell

Keywords - Cellular componenti

Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001416181 – 108Glutaredoxin-1Add BLAST108

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi23 ↔ 26Redox-activeBy similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliP68692
SMRiP68692
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 106GlutaredoxinPROSITE-ProRule annotationAdd BLAST104

Sequence similaritiesi

Belongs to the glutaredoxin family.Curated

Keywords - Domaini

Redox-active center

Phylogenomic databases

OrthoDBiVOG090001AI

Family and domain databases

InterProiView protein in InterPro
IPR011767 GLR_AS
IPR002109 Glutaredoxin
IPR011899 Glutaredoxin_euk/vir
IPR014025 Glutaredoxin_subgr
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00462 Glutaredoxin, 1 hit
PRINTSiPR00160 GLUTAREDOXIN
SUPFAMiSSF52833 SSF52833, 1 hit
TIGRFAMsiTIGR02180 GRX_euk, 1 hit
PROSITEiView protein in PROSITE
PS00195 GLUTAREDOXIN_1, 1 hit
PS51354 GLUTAREDOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

P68692-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEEFVQQRL ANNKVTIFVK YTCPFCRNAL DILNKFSFKR GAYEIVDIKE
60 70 80 90 100
FKPENELRDY FEQITGGRTV PRIFFGKTSI GGYSDLLEID NMDALGDILS

SIGVLRTC
Length:108
Mass (Da):12,355
Last modified:December 7, 2004 - v1
Checksum:i8C754AE57D7F54D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M76472 Genomic DNA Translation: AAA48249.1
AY243312 Genomic DNA Translation: AAO89348.1
PIRiE42510
RefSeqiYP_232951.1, NC_006998.1

Genome annotation databases

GeneIDi3707602
KEGGivg:3707602

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M76472 Genomic DNA Translation: AAA48249.1
AY243312 Genomic DNA Translation: AAO89348.1
PIRiE42510
RefSeqiYP_232951.1, NC_006998.1

3D structure databases

ProteinModelPortaliP68692
SMRiP68692
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3707602
KEGGivg:3707602

Phylogenomic databases

OrthoDBiVOG090001AI

Family and domain databases

InterProiView protein in InterPro
IPR011767 GLR_AS
IPR002109 Glutaredoxin
IPR011899 Glutaredoxin_euk/vir
IPR014025 Glutaredoxin_subgr
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00462 Glutaredoxin, 1 hit
PRINTSiPR00160 GLUTAREDOXIN
SUPFAMiSSF52833 SSF52833, 1 hit
TIGRFAMsiTIGR02180 GRX_euk, 1 hit
PROSITEiView protein in PROSITE
PS00195 GLUTAREDOXIN_1, 1 hit
PS51354 GLUTAREDOXIN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGLRX1_VACCW
AccessioniPrimary (citable) accession number: P68692
Secondary accession number(s): P20818
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 7, 2004
Last sequence update: December 7, 2004
Last modified: October 10, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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