O2L

Functionⁱ

Displays thioltransferase and dehydroascorbate reductase activities.By similarity

GO - Molecular functionⁱ

electron transfer activity Source: InterPro
protein disulfide oxidoreductase activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell redox homeostasis Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Electron transport, Transport

Biological process

Electron transport, Transport

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Glutaredoxin-1
Gene namesⁱ	ORF Names:O2L
Organismⁱ	Vaccinia virus (strain Copenhagen) (VACV)
Taxonomic identifierⁱ	10249 [NCBI]
Taxonomic lineageⁱ	Viruses › dsDNA viruses, no RNA stage › Poxviridae › Chordopoxvirinae › Orthopoxvirus › Vaccinia virus
Virus hostⁱ	Homo sapiens (Human) [TaxID: 9606]
Proteomesⁱ	UP000008269 Componentⁱ: Genome

Subcellular locationⁱ

Virion

Note:

Localizes to the virion core.By similarity

GO - Cellular componentⁱ

virion Source: UniProtKB-SubCell

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Virion

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000141615	1 – 108	Glutaredoxin-1Add BLAST		108

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Disulfide bondⁱ	23 ↔ 26	Redox-activeBy similarity

Keywords - PTMⁱ

Disulfide bond

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P68690
SMRⁱ	P68690
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	3 – 106	GlutaredoxinPROSITE-ProRule annotationAdd BLAST		104

Sequence similaritiesⁱ

Belongs to the glutaredoxin family.Curated

Keywords - Domainⁱ

Redox-active center

Phylogenomic databases

Database of Orthologous Groups More...OrthoDBⁱ	VOG090001AI

OrthoDBⁱ

VOG090001AI

Family and domain databases

InterProⁱ	View protein in InterPro IPR011767 GLR_AS IPR002109 Glutaredoxin IPR011899 Glutaredoxin_euk/vir IPR014025 Glutaredoxin_subgr IPR036249 Thioredoxin-like_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00462 Glutaredoxin, 1 hit
PRINTSⁱ	PR00160 GLUTAREDOXIN
SUPFAMⁱ	SSF52833 SSF52833, 1 hit
TIGRFAMsⁱ	TIGR02180 GRX_euk, 1 hit
PROSITEⁱ	View protein in PROSITE PS00195 GLUTAREDOXIN_1, 1 hit PS51354 GLUTAREDOXIN_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P68690-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAEEFVQQRL ANNKVTIFVK YTCPFCRNAL DILNKFSFKR GAYEIVDIKE 
        60         70         80         90        100
FKPENELRDY FEQITGGRTV PRIFFGKTSI GGYSDLLEID NMDALGDILS 

SIGVLRTC

Length:108

Mass (Da):12,355

Last modified:December 7, 2004 - v1

Checksum:ⁱ8C754AE57D7F54D4

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M35027 Genomic DNA Translation: AAA48055.1
PIRⁱ	E42510

Protein	Similar proteins		Species	Score	Length	Source
P68690	Glutaredoxin-1		VACCA		108	UniRef100_Q76ZV3
Glutaredoxin-1		RABPU		108
Glutaredoxin-1		VACCP		108
Glutaredoxin-1		VACCT		108
Glutaredoxin-1		VACCW		108
+6

Protein	Similar proteins		Species	Score	Length	Source
P68690	Glutaredoxin-1		VACCA		108	UniRef90_Q76ZV3
Glutaredoxin-1		RABPU		108
Glutaredoxin-1		VACCP		108
Glutaredoxin-1		VACCT		108
Glutaredoxin-1		VACCW		108
+35

Protein	Similar proteins		Species	Score	Length	Source
P68690	Glutaredoxin-1		VACCA		108	UniRef50_Q76ZV3
Glutaredoxin-1		RABPU		108
Glutaredoxin-1		VACCP		108
Glutaredoxin-1		VACCT		108
Glutaredoxin-1		VACCW		108
+41

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M35027 Genomic DNA Translation: AAA48055.1
PIRⁱ	E42510

3D structure databases

ProteinModelPortalⁱ	P68690
SMRⁱ	P68690
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Phylogenomic databases

OrthoDBⁱ	VOG090001AI

OrthoDBⁱ

VOG090001AI

Family and domain databases

InterProⁱ	View protein in InterPro IPR011767 GLR_AS IPR002109 Glutaredoxin IPR011899 Glutaredoxin_euk/vir IPR014025 Glutaredoxin_subgr IPR036249 Thioredoxin-like_sf
Pfamⁱ	View protein in Pfam PF00462 Glutaredoxin, 1 hit
PRINTSⁱ	PR00160 GLUTAREDOXIN
SUPFAMⁱ	SSF52833 SSF52833, 1 hit
TIGRFAMsⁱ	TIGR02180 GRX_euk, 1 hit
PROSITEⁱ	View protein in PROSITE PS00195 GLUTAREDOXIN_1, 1 hit PS51354 GLUTAREDOXIN_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	GLRX1_VACCC
Accessionⁱ	P68690Primary (citable) accession number: P68690 Secondary accession number(s): P20818
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 7, 2004
	Last sequence update:	December 7, 2004
	Last modified:	October 10, 2018
	This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Viral Protein Annotation Program

UniProtKB - P68690 (GLRX1_VACCC)

Your basket is currently empty. ⁱ

Glutaredoxin-1

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Molecule processing

Amino acid modifications

Keywords - PTMⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P68690 (GLRX1_VACCC)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Glutaredoxin-1

O2L

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ