UniProtKB - P68690 (GLRX1_VACCC)
Protein
Glutaredoxin-1
Gene
O2L
Organism
Vaccinia virus (strain Copenhagen) (VACV)
Status
Functioni
Displays thioltransferase and dehydroascorbate reductase activities.By similarity
GO - Molecular functioni
- electron transfer activity Source: InterPro
- protein disulfide oxidoreductase activity Source: InterPro
GO - Biological processi
- cell redox homeostasis Source: InterPro
Keywordsi
Biological process | Electron transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Glutaredoxin-1 |
Gene namesi | ORF Names:O2L |
Organismi | Vaccinia virus (strain Copenhagen) (VACV) |
Taxonomic identifieri | 10249 [NCBI] |
Taxonomic lineagei | Viruses › dsDNA viruses, no RNA stage › Poxviridae › Chordopoxvirinae › Orthopoxvirus › Vaccinia virus |
Virus hosti | Homo sapiens (Human) [TaxID: 9606] |
Proteomesi |
|
Subcellular locationi
- Virion Note: Localizes to the virion core.By similarity
GO - Cellular componenti
Keywords - Cellular componenti
VirionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000141615 | 1 – 108 | Glutaredoxin-1Add BLAST | 108 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 23 ↔ 26 | Redox-activeBy similarity |
Keywords - PTMi
Disulfide bondStructurei
3D structure databases
ProteinModelPortali | P68690 |
SMRi | P68690 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 3 – 106 | GlutaredoxinPROSITE-ProRule annotationAdd BLAST | 104 |
Sequence similaritiesi
Belongs to the glutaredoxin family.Curated
Keywords - Domaini
Redox-active centerFamily and domain databases
InterProi | View protein in InterPro IPR011767 GLR_AS IPR002109 Glutaredoxin IPR011899 Glutaredoxin_euk/vir IPR014025 Glutaredoxin_subgr IPR036249 Thioredoxin-like_sf |
Pfami | View protein in Pfam PF00462 Glutaredoxin, 1 hit |
PRINTSi | PR00160 GLUTAREDOXIN |
SUPFAMi | SSF52833 SSF52833, 1 hit |
TIGRFAMsi | TIGR02180 GRX_euk, 1 hit |
PROSITEi | View protein in PROSITE PS00195 GLUTAREDOXIN_1, 1 hit PS51354 GLUTAREDOXIN_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P68690-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEEFVQQRL ANNKVTIFVK YTCPFCRNAL DILNKFSFKR GAYEIVDIKE
60 70 80 90 100
FKPENELRDY FEQITGGRTV PRIFFGKTSI GGYSDLLEID NMDALGDILS
SIGVLRTC
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M35027 Genomic DNA Translation: AAA48055.1 |
PIRi | E42510 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M35027 Genomic DNA Translation: AAA48055.1 |
PIRi | E42510 |
3D structure databases
ProteinModelPortali | P68690 |
SMRi | P68690 |
ModBasei | Search... |
MobiDBi | Search... |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Family and domain databases
InterProi | View protein in InterPro IPR011767 GLR_AS IPR002109 Glutaredoxin IPR011899 Glutaredoxin_euk/vir IPR014025 Glutaredoxin_subgr IPR036249 Thioredoxin-like_sf |
Pfami | View protein in Pfam PF00462 Glutaredoxin, 1 hit |
PRINTSi | PR00160 GLUTAREDOXIN |
SUPFAMi | SSF52833 SSF52833, 1 hit |
TIGRFAMsi | TIGR02180 GRX_euk, 1 hit |
PROSITEi | View protein in PROSITE PS00195 GLUTAREDOXIN_1, 1 hit PS51354 GLUTAREDOXIN_2, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | GLRX1_VACCC | |
Accessioni | P68690Primary (citable) accession number: P68690 Secondary accession number(s): P20818 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 7, 2004 |
Last sequence update: | December 7, 2004 | |
Last modified: | February 13, 2019 | |
This is version 65 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteomeDocuments
- SIMILARITY comments
Index of protein domains and families