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Graphical

Stress granuleCytoplasmCytoplasmic ribonucleoprotein granule

Definition

Stress granules are dense non-membrane bound aggregations in the cytosol composed of proteins and RNAs that appear when the cell is under stress. The aggregates are mostly composed of stalled translation initiation complexes. They are 100-200 nm in size. Stress granules can also precipitate the formation of toxic protein aggregates such as those seen during the progression of certain types of neurological disease.

Category

› Cellular component

GOi

cytoplasmic stress granule [ GO:0010494 ]

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