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Protein

Probable acyl-activating enzyme 8

Gene

AAE8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May act as an acid--thiol ligase that activates carboxylic acids by forming acyl-CoAs.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processFatty acid metabolism, Lipid metabolism

Enzyme and pathway databases

BioCyciARA:AT1G75960-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acyl-activating enzyme 8 (EC:6.2.1.-)
Alternative name(s):
AMP-binding protein 8
Short name:
AtAMPBP8
Gene namesi
Name:AAE8
Synonyms:AMPBP8
Ordered Locus Names:At1g75960
ORF Names:T4O12.18
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G75960.
TAIRilocus:2204360. AT1G75960.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004157191 – 544Probable acyl-activating enzyme 8Add BLAST544

Proteomic databases

PaxDbiQ9LQS1.

PTM databases

iPTMnetiQ9LQS1.

Expressioni

Tissue specificityi

Expressed at low levels in roots, leaves, stems, flowers and developing seeds.1 Publication

Gene expression databases

GenevisibleiQ9LQS1. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G75960.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LQS1.
SMRiQ9LQS1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1176. Eukaryota.
COG0318. LUCA.
HOGENOMiHOG000230005.
InParanoidiQ9LQS1.
OMAiECTAPCA.
OrthoDBiEOG093608HH.
PhylomeDBiQ9LQS1.

Family and domain databases

InterProiView protein in InterPro
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
PfamiView protein in Pfam
PF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
PROSITEiView protein in PROSITE
PS00455. AMP_BINDING. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9LQS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDLKPSAAN SLPLTLLGFL ERAATVYGDC TSIVYGNSTV YTWRETNHRC
60 70 80 90 100
LCVASALSSI GIGRSDVVSV LSANTPEMYE LQFSVPMSGA ILNNINTRLD
110 120 130 140 150
ARTVSVLLRH CESKLLFVDF FYSDLAVEAI TMLLNPPILV LIANEEEEEG
160 170 180 190 200
GAEVTERSKF CYLYSDLITR GNPDFKWIRP GSEWDPIVVN YTSGTTSSPK
210 220 230 240 250
GVVHCHRGIF VMTLDSLTDW AVPKTPVYLW TLPIFHANGW TYPWGIAAVG
260 270 280 290 300
GTNVCVRKLH APSIYHLIRD HGVTHMYGAP IVLQILSASQ ESDQPLKSPV
310 320 330 340 350
NFLTAGSSPP ATVLLRAESL GFIVSHGYGL TETAGVIVSC AWKPNWNRLP
360 370 380 390 400
ASDQAQLKSR QGVRTVGFSE IDVVDPESGR SVERDGETVG EIVLRGSSIM
410 420 430 440 450
LGYLKNPIGT QNSFKNGWFF TGDLGVIHGD GYLEIKDRSK DVIISGGENV
460 470 480 490 500
SSVEVEAVLY TNPAVNEAAV VARPDEFWGE TPCAFVSLKP GLTRKPTDKE
510 520 530 540
IIEYCKYKMP RYMAPKTVSF LEELPKTSTG KIIKSLLKEI AKNM
Length:544
Mass (Da):59,711
Last modified:October 1, 2000 - v1
Checksum:i8A22CF91AFB3C66B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti3 – 5DLK → E in AAM28625 (PubMed:12177484).Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF503767 mRNA. Translation: AAM28625.1.
AC007396 Genomic DNA. Translation: AAF26762.1.
CP002684 Genomic DNA. Translation: AEE35781.1.
AY070450 mRNA. Translation: AAL49853.1.
AY142663 mRNA. Translation: AAN13201.1.
RefSeqiNP_177724.1. NM_106246.4.
UniGeneiAt.28351.
At.67201.
At.71895.

Genome annotation databases

EnsemblPlantsiAT1G75960.1; AT1G75960.1; AT1G75960.
GeneIDi843929.
GrameneiAT1G75960.1; AT1G75960.1; AT1G75960.
KEGGiath:AT1G75960.

Similar proteinsi

Entry informationi

Entry nameiAAE8_ARATH
AccessioniPrimary (citable) accession number: Q9LQS1
Secondary accession number(s): Q8LRT4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: October 1, 2000
Last modified: June 7, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families