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Protein

Probable acyl-activating enzyme 4

Gene

AEE4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May act as an acid--thiol ligase that activates carboxylic acids by forming acyl-CoAs.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processFatty acid metabolism, Lipid metabolism

Enzyme and pathway databases

BioCyciARA:GQT-590-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable acyl-activating enzyme 4 (EC:6.2.1.-)
Alternative name(s):
AMP-binding protein 4
Short name:
AtAMPBP4
Gene namesi
Name:AEE4
Synonyms:AMPBP4
Ordered Locus Names:At1g77240
ORF Names:T14N5.10
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G77240.
TAIRilocus:2195950. AT1G77240.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004157151 – 545Probable acyl-activating enzyme 4Add BLAST545

Proteomic databases

PaxDbiO80658.
PRIDEiO80658.

Expressioni

Tissue specificityi

Expressed in roots, leaves, stems, flowers and developing seeds.1 Publication

Gene expression databases

ExpressionAtlasiO80658. baseline and differential.
GenevisibleiO80658. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G77240.1.

Structurei

3D structure databases

ProteinModelPortaliO80658.
SMRiO80658.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1176. Eukaryota.
COG0318. LUCA.
HOGENOMiHOG000230005.
InParanoidiO80658.
OMAiVRPKSEW.
OrthoDBiEOG093608HH.
PhylomeDBiO80658.

Family and domain databases

InterProiView protein in InterPro
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
PfamiView protein in Pfam
PF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
PROSITEiView protein in PROSITE
PS00455. AMP_BINDING. 1 hit.

Sequencei

Sequence statusi: Complete.

O80658-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELLLPHASN SCPLTVLGFL ERAASVFGDS PSLLHTTTVH TWSETHSRCL
60 70 80 90 100
RIASTLSSAS LGINRGQVVS VIGPNVPSVY ELQFAVPMSG AVLNNINPRL
110 120 130 140 150
DAHALSVLLR HSESKLVFVD HHSSSLVLEA VSFLPKDERP RLVILNDGND
160 170 180 190 200
MPSSSSADMD FLDTYEGFME RGDLRFKWVR PKSEWTPMVL NYTSGTTSSP
210 220 230 240 250
KGVVHSHRSV FMSTINSLLD WSLPNRPVYL WTLPMFHANG WSYTWATAAV
260 270 280 290 300
GARNICVTRV DVPTIFNLID KYQVTHMCAA PMVLNMLTNH PAQKPLQSPV
310 320 330 340 350
KVMTAGAPPP ATVISKAEAL GFDVSHGYGM TETGGLVVSC ALKPEWDRLE
360 370 380 390 400
PDERAKQKSR QGIRTAVFAE VDVRDPISGK SVKHDGATVG EIVFRGGSVM
410 420 430 440 450
LGYYKDPEGT AASMREDGWF YTGDIGVMHP DGYLEVKDRS KDVVICGGEN
460 470 480 490 500
ISSTELEAVL YTNPAIKEAA VVAKPDKMWG ETPCAFVSLK YHDGSVTERE
510 520 530 540
IREFCKTKLP KYMVPRNVVF LEELPKTSTG KIQKFLLRQM AKSLP
Length:545
Mass (Da):60,011
Last modified:November 1, 1998 - v1
Checksum:i22CF3108903E6669
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti123S → L in AAM28621 (PubMed:12177484).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF503763 mRNA. Translation: AAM28621.1.
AC004260 Genomic DNA. Translation: AAC34346.1.
CP002684 Genomic DNA. Translation: AEE35953.1.
PIRiT00453.
RefSeqiNP_177848.1. NM_106373.2.
UniGeneiAt.34523.
At.75598.

Genome annotation databases

EnsemblPlantsiAT1G77240.1; AT1G77240.1; AT1G77240.
GeneIDi844060.
GrameneiAT1G77240.1; AT1G77240.1; AT1G77240.
KEGGiath:AT1G77240.

Similar proteinsi

Entry informationi

Entry nameiAAE4_ARATH
AccessioniPrimary (citable) accession number: O80658
Secondary accession number(s): Q8LRT5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: November 1, 1998
Last modified: July 5, 2017
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families