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Protein

Accessory gland protein Acp53Ea

Gene

Acp53Ea

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Responsible for physiological and behavioral changes in mated female flies.1 Publication

GO - Biological processi

  • behavior Source: UniProtKB-KW
  • multicellular organism reproduction Source: FlyBase
  • sperm competition Source: FlyBase

Keywordsi

Biological processBehavior

Names & Taxonomyi

Protein namesi
Recommended name:
Accessory gland protein Acp53Ea
Gene namesi
Name:Acp53Ea
ORF Names:CG8622
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0015584. Acp53Ea.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000002058424 – 120Accessory gland protein Acp53EaAdd BLAST97

Proteomic databases

PaxDbiO46199.
PRIDEiO46199.

Expressioni

Tissue specificityi

Main cells of accessory gland and seminal fluid.1 Publication

Gene expression databases

BgeeiFBgn0015584.
GenevisibleiO46199. DM.

Interactioni

Protein-protein interaction databases

BioGridi62583. 2 interactors.
DIPiDIP-22625N.
IntActiO46199. 1 interactor.
MINTiMINT-854671.
STRINGi7227.FBpp0086228.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiO46199.
OMAiWLACNRI.
OrthoDBiEOG091G0XJO.
PhylomeDBiO46199.

Family and domain databases

InterProiView protein in InterPro
IPR009392. ACP53EA.
PfamiView protein in Pfam
PF06313. ACP53EA. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O46199-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLIKVTLVF SLLALVFVAQ TEAQNPIWEN WLACNRIGTK ALASLLRETI
60 70 80 90 100
PTVRNLLNCI DFNPPTDIGN SYLSKLKLYY ELVKRGALDK TQCLIVPLKE
110 120
SVRLLRPYVK SLETNKCLGE
Length:120
Mass (Da):13,607
Last modified:June 1, 1998 - v1
Checksum:iC576B846B4DC2871
GO

Sequence cautioni

O46199: The sequence AAM29231 differs from that shown. Reason: Frameshift at position 10.Curated
O46199: The sequence AAM29231 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti7T → A in strain: ZIM56. 1
Natural varianti14A → D in strain: M47. 1
Natural varianti21T → L in strain: M47. 1
Natural varianti22E → K in strain: ZIM26 and ZIM42. 1
Natural varianti27I → V in strain: ZIM56. 1
Natural varianti70N → K in strain: M09 and WS9. 1
Natural varianti72Y → C in strain: SFS 3.1. 1
Natural varianti83V → D in strain: ZIM30. 1
Natural varianti108Y → C in strain: ZIM2. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U85760 mRNA. Translation: AAB96384.1.
AY010593 Genomic DNA. Translation: AAG37375.1.
AY010594 Genomic DNA. Translation: AAG37376.1.
AY010595 Genomic DNA. Translation: AAG37377.1.
AY010596 Genomic DNA. Translation: AAG37378.1.
AY010597 Genomic DNA. Translation: AAG37379.1.
AY010598 Genomic DNA. Translation: AAG37380.1.
AY010599 Genomic DNA. Translation: AAG37381.1.
AY010600 Genomic DNA. Translation: AAG37382.1.
AY010601 Genomic DNA. Translation: AAG37383.1.
AY010602 Genomic DNA. Translation: AAG37384.1.
AY010603 Genomic DNA. Translation: AAG37385.1.
AY010604 Genomic DNA. Translation: AAG37386.1.
AY010605 Genomic DNA. Translation: AAG37387.1.
AY010606 Genomic DNA. Translation: AAG37388.1.
AY010607 Genomic DNA. Translation: AAG37389.1.
AY344265 Genomic DNA. Translation: AAR04580.1.
AY344266 Genomic DNA. Translation: AAR04581.1.
AY344267 Genomic DNA. Translation: AAR04582.1.
AY344268 Genomic DNA. Translation: AAR04583.1.
AY344269 Genomic DNA. Translation: AAR04584.1.
AY344270 Genomic DNA. Translation: AAR04585.1.
AY344271 Genomic DNA. Translation: AAR04586.1.
AY344272 Genomic DNA. Translation: AAR04587.1.
AY344273 Genomic DNA. Translation: AAR04588.1.
AY344274 Genomic DNA. Translation: AAR04589.1.
AY344275 Genomic DNA. Translation: AAR04590.1.
AY344276 Genomic DNA. Translation: AAR04591.1.
AY344277 Genomic DNA. Translation: AAR04592.1.
AY344278 Genomic DNA. Translation: AAR04593.1.
AY344279 Genomic DNA. Translation: AAR04594.1.
AY344280 Genomic DNA. Translation: AAR04595.1.
AY344281 Genomic DNA. Translation: AAR04596.1.
AY344282 Genomic DNA. Translation: AAR04597.1.
AY344283 Genomic DNA. Translation: AAR04598.1.
AY344284 Genomic DNA. Translation: AAR04599.1.
AY635241 Genomic DNA. Translation: AAT49147.1.
AY635242 Genomic DNA. Translation: AAT49148.1.
AY635243 Genomic DNA. Translation: AAT49149.1.
AY635244 Genomic DNA. Translation: AAT49150.1.
AY635245 Genomic DNA. Translation: AAT49151.1.
AY635246 Genomic DNA. Translation: AAT49152.1.
AE013599 Genomic DNA. Translation: AAF57959.1.
AY113226 mRNA. Translation: AAM29231.1. Frameshift.
RefSeqiNP_477151.1. NM_057803.5.
UniGeneiDm.19942.

Genome annotation databases

EnsemblMetazoaiFBtr0087080; FBpp0086228; FBgn0015584.
GeneIDi36874.
KEGGidme:Dmel_CG8622.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiA53E_DROME
AccessioniPrimary (citable) accession number: O46199
Secondary accession number(s): Q6GUV6
, Q6VBF9, Q6VBG0, Q6VBG1, Q8MZD8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: June 1, 1998
Last modified: October 25, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase