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Protein

1-aminocyclopropane-1-carboxylate deaminase

Gene

acdS

Organism
Agrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain S4))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.UniRule annotation

Catalytic activityi

1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH3.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei77NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandPyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
1-aminocyclopropane-1-carboxylate deaminaseUniRule annotation (EC:3.5.99.7UniRule annotation)
Short name:
ACC deaminaseUniRule annotation
Short name:
ACCDUniRule annotation
Gene namesi
Name:acdSUniRule annotation
Ordered Locus Names:Avi_5856
OrganismiAgrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain S4))
Taxonomic identifieri311402 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacterium
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001485751 – 3371-aminocyclopropane-1-carboxylate deaminaseAdd BLAST337

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei50N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Subunit structurei

Homotrimer.UniRule annotation

Protein-protein interaction databases

STRINGi311402.Avi_5856

Structurei

3D structure databases

SMRiB9K206
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ACC deaminase/D-cysteine desulfhydrase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105K6H Bacteria
COG2515 LUCA
HOGENOMiHOG000022460
KOiK01505
OMAiAKIGMKC
OrthoDBiPOG091H0N3P

Family and domain databases

HAMAPiMF_00807 ACC_deaminase, 1 hit
InterProiView protein in InterPro
IPR027278 ACCD_DCysDesulf
IPR005965 ACP_carboxylate_deaminase
IPR020601 ACP_carboxylate_deaminase_bac
IPR001926 PLP-dep
IPR036052 Trypto_synt_PLP_dependent
PfamiView protein in Pfam
PF00291 PALP, 1 hit
PIRSFiPIRSF006278 ACCD_DCysDesulf, 1 hit
SUPFAMiSSF53686 SSF53686, 1 hit
TIGRFAMsiTIGR01274 ACC_deam, 1 hit

Sequencei

Sequence statusi: Complete.

B9K206-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDAFDRYPL TFGPTPIEKL ERLTDHLGGK VQLYAKREDC NSGLAFGGNK
60 70 80 90 100
LRKLEYIIPD AIASGADTLV SIGGVQSNHT RMVAAVAAKI GFKCRLVQEA
110 120 130 140 150
WVPHEDAVYD RVGNIMLSRI MGADVRLVDD GFDIGIRRSW EEAIEEVKAA
160 170 180 190 200
GGKPYAIPAG ASVHKYGGLG YVGFAEEVRA QEAALGFAFD YIVVCTVTGS
210 220 230 240 250
SHAGMAVGFA KDGRADHVIG IDASFTPDQT RAQVLEIAQR TADLVKLGRE
260 270 280 290 300
MRPEDIVLVE DYAYPVYGVP SEETKDAIRL VGRLEGMITD PVYEGKSMQG
310 320 330
MIDLVKKGYF PEGSKVLYAH LGGAPALNGY GYAFRNG
Length:337
Mass (Da):36,472
Last modified:March 24, 2009 - v1
Checksum:i9828FC50CC0143AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000634 Genomic DNA Translation: ACM38904.1
RefSeqiWP_012654146.1, NC_011988.1

Genome annotation databases

EnsemblBacteriaiACM38904; ACM38904; Avi_5856
GeneIDi31497822
KEGGiavi:Avi_5856

Entry informationi

Entry namei1A1D_AGRVS
AccessioniPrimary (citable) accession number: B9K206
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 23, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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