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Protein

p-hydroxybenzoic acid efflux pump subunit AaeA

Gene

aaeA

Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms an efflux pump with AaeB.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
p-hydroxybenzoic acid efflux pump subunit AaeAUniRule annotation
Short name:
pHBA efflux pump protein AUniRule annotation
Gene namesi
Name:aaeAUniRule annotation
Ordered Locus Names:EFER_3219
OrganismiEscherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Taxonomic identifieri585054 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000745 Componenti: Chromosome

Subcellular locationi

B7LRL6:
  • Cell inner membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001467201 – 310p-hydroxybenzoic acid efflux pump subunit AaeAAdd BLAST310

Expressioni

Inductioni

Positively coregulated with aaeB and aaeX by AaeR.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7LRL6.
SMRiB7LRL6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000112073.
KOiK15548.
OMAiYLLAYME.
OrthoDBiPOG091H0I3Z.

Family and domain databases

HAMAPiMF_01544. AaeA. 1 hit.
InterProiView protein in InterPro
IPR022871. PHBA_efflux_pump_AaeA.
IPR006143. RND_pump_MFP.
TIGRFAMsiTIGR01730. RND_mfp. 1 hit.

Sequencei

Sequence statusi: Complete.

B7LRL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLIRKLTR TAITLVLVIL AFIAIFRAWV YYTESPWTRD ARFSADVVAI
60 70 80 90 100
APDVAGLITN VNVHDNQLVK KGQVLFTIDQ PRYQKALAEA EADVAYYSVL
110 120 130 140 150
AQEKRQEASR RNRLGVQAMS REEIDQANNV LQTVLHQLAK AQATRDLAKL
160 170 180 190 200
DLERTVIRAP ADGWVTNLNV YTGEFITRGS TAVALVKQNT FYVLAYMEET
210 220 230 240 250
KLEGVRPGYR AEITPLGSNR VLKGTVDSIA AGVTNASSTR DAKGMATIDS
260 270 280 290 300
NLEWVRLAQR VPVRIRLDAQ PENLWPAGTT ATVVVTGKDD RDESQDSFFR
310
KMAHRLREFG
Length:310
Mass (Da):34,624
Last modified:February 10, 2009 - v1
Checksum:i42A7DC50A1E60ADA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928158 Genomic DNA. Translation: CAQ90712.1.
RefSeqiWP_000854043.1. NC_011740.1.

Genome annotation databases

EnsemblBacteriaiCAQ90712; CAQ90712; EFER_3219.
KEGGiefe:EFER_3219.

Similar proteinsi

Entry informationi

Entry nameiAAEA_ESCF3
AccessioniPrimary (citable) accession number: B7LRL6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: September 27, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families